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Hematology is the study of blood and the disorders related to it. Human blood is composed of ∼45% cellular components and ∼55% plasma. Blood has many functions, including transporting oxygen, regulating body temperature, and supporting the immune system.
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The cellular component consists of three major cell types, all of which arise from hematopoietic stem cells located primarily in the bone marrow: red blood cells (RBCs), white blood cells (WBCs), and platelets. Red blood cells (RBC, erythrocytes) are hemoglobin-carrying cells that primarily transport oxygen. White blood cells (WBC, leukocytes) take the form of either granulocytes or lymphocytes. Granulocytes are part of the innate immune system and play a key role in the immune response to bacteria, fungi, and parasites. Lymphocytes are highly antigen-specific, meaning they are able to target specific infectious agents, primarily viruses. Platelets are the other major cellular component of blood and are small anucleate cells produced from megakaryocytes in the bone marrow. This learning card provides an overview of the production, morphology, and most important functions of blood cells.
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